Charcot Marie Tooth (CMT) disease, a progressive peripheral motor and sensory neuropathy, poses significant challenges for affected individuals. It leads to gradual onset of weakness and muscle atrophy in the foot and leg, often accompanied by foot deformities. Therefore, it substantially impacts mobility and stability, consequently diminishing quality of life. Moreover, most patients complain of walking-related pain.
Successful treatments follow appropriate assessment
At Sol et Salus Hospital, we specialize in treating patients with CMT with neuro-orthopedic surgery. Our approach customizes surgical interventions, involving procedures targeting soft tissues or bones, based on detailed instrumental gait analysis. Despite the rarity of the disease, our extensive repository of patient data, meticulously collected over years of dedicated care, serves as a cornerstone for our ongoing research pursuits.
Short-term effects of surgery on pain and satisfaction
We recently published a study investigating the short-term effects of neuro-orthopedic surgery on walking-related pain among patients with CMT. Using gait analysis, we also examined changes in the progression of the center of pressure during walking, derived from force platform data. Finally, we assessed patients’ functional abilities and their perceived improvement. Most patients experienced a notable reduction in pain, particularly those with higher preoperative pain levels. Statistical analysis revealed significant improvements in the progression of the center of pressure, likely attributed to corrected foot deformities. Although functional abilities did not show significant enhancement, overall patient satisfaction was high.
Open-access full-text is available here.
Research and consulting: MBE milestones
At MerloBioEngineering, we take great pride in collaborating with institutions dedicated to improving the lives of individuals affected by rare diseases like CMT. At Sol et Salus Hospital, with great teamwork, we conduct thorough pre-operative assessments involving instrumental gait analysis inclusive of surface electromyography, enabling personalized treatment planning.
Our support extends beyond clinical realms. We actively support research endeavors by curating and managing appropriate databases, fostering scientific dissemination, and facilitating the publication of groundbreaking discoveries.
